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By Mayo Clinic staffPeyronie's disease is the development of abnormal scar tissue, or plaques, in tissues inside the penis. When a penis affected by Peyronie's (pa-ro-NEEZ) disease is erect, it's usually bent and may be painful.
Peyronie's disease may prevent a man from having sex, and men with Peyronie's disease often experience stress or anxiety related to this disorder.
Research about the effectiveness of nonsurgical treatments for Peyronie's disease is limited. Surgery to correct a curved or bent penis is usually recommended if the deformity is severe or prevents satisfactory sexual activity.
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