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Complications
By Mayo Clinic staffSeveral conditions may result from premature ovarian failure:
- Infertility. Infertility is a troubling challenge for many women with premature ovarian failure. Yet, a very small percentage of women with the condition may become pregnant and deliver healthy babies, so natural conception remains a small possibility.
- Osteoporosis. The hormone estrogen helps maintain strong bones. Women with low levels of estrogen are at an increased risk of developing weak and brittle bones (osteoporosis), which are more likely to break than are healthy bones.
- Depression or anxiety. The risk of infertility and other complications arising from low estrogen levels may cause some women to become anxious or depressed.
References
- Cedars M, et al. Premature ovarian failure. Journal of Clinical Endocrinology and Metabolism. 2008;93:i.
- Do I have premature ovarian failure (POF)? National Institute of Child Health and Human Development. http://www.nichd.nih.gov/publications/pubs/pof/sub1.cfm#what. Accessed Dec. 1, 2008.
- Lobo RA. Menopause: Endocrinology, consequences of estrogen deficiency, effects of hormone replacement therapy, treatment regimens. In: Katz VL, et al. Comprehensive Gynecology. 5th ed. Philadelphia, Pa.: Mosby Elsevier; 2007. http://www.mdconsult.com/das/book/body/112160892-5/778264621/1524/277.html#4-u1.0-B978-0-323-02951-3..50045-5--cesec1_1347. Accessed Dec. 1, 2008.
- Welt CK. Pathogenesis and causes of spontaneous premature ovarian failure. http://www.uptodate.com/home/index.html. Accessed Nov. 25, 2008.
- Bulun SE, et al. The physiology and pathology of the female reproductive axis. In: Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/112160892-6/778264621/1555/106.html#4-u1.0-B978-1-4160-2911-3..50018-2--cesec91_1490. Accessed Dec. 1, 2008.
- Kalu E, et al. Spontaneous premature ovarian failure: Management challenges. Gynecological Endocrinology. 2008;24:273.
- Nelson LM, et al. Evaluation of spontaneous premature ovarian failure. http://www.uptodate.com/home/index.html. Accessed Nov. 25, 2008.
- Nelson LM, et al. Management of spontaneous premature ovarian failure. http://www.uptodate.com/home/index.html. Accessed Nov. 25, 2008.
