Mayo Clinic Health Manager
Get free personalized health guidance for you and your family.
Get Started
About our e-newsletters
- Free e-newsletters
- Mayo Clinic expertise
- We do not share your e-mail address
Housecall, our weekly general-interest e-newsletter, keeps you up to date on a wide variety of health topics with timely, reliable, practical information, recipes, blogs, questions and answers with Mayo Clinic experts and more. Our biweekly topic-specific e-newsletters also include blogs, questions and answers with Mayo Clinic experts, and other useful information that will help you manage your health.
Housecall Archives
Mayo Clinic Housecall
Stay up to date on the latest health information.
What you get
- Free weekly e-newsletter
- Mayo Clinic expertise
- Recipes, tools and other helpful information
- We do not share your e-mail address
Preparing for your appointment
By Mayo Clinic staffYour doctor may first suspect primary aldosteronism if you have high blood pressure and low blood potassium, although many people with this condition have normal potassium levels, especially in the early stages of the disease.
To diagnose primary aldosteronism, you'll need certain tests. Your doctor is likely to begin by measuring the levels of aldosterone and renin in your blood. Renin is an enzyme released by your kidneys that helps regulate blood pressure. The combination of a very low renin level with a high aldosterone level indicates that primary aldosteronism may be the cause of your high blood pressure.
This test can be performed while you're taking most blood pressure medications, but you'll need to discontinue taking drugs such as spironolactone and eplerenone six weeks before testing. Your doctor may also recommend avoiding other medications, including some over-the-counter pain relievers, and following a low-sodium diet before you take the test.
- Funder JW, et al. Case detection, diagnosis and treatment of patients with primary aldosteronism: An Endocrine Society clinical practice guideline. Journal of Clinical Endocrinology & Metabolism. 2008;(93):3266-3281.
- Gomez-Sanchez CE, et al. Three perspectives on aldosterone's role in cardiovascular disease: Salt's not the only bad guy. The Endocrine Society. http://www.endo-society.org/endo_news/tri_point/upload/Tri-Point-Series-June-2005-EN.pdf. Accessed Sept. 25, 2008.
- Young WF, et al. Clinical features of primary aldosteronism. http://www.uptodate.com/home/index.html. Accessed Sept. 25, 2008.
- Hyperaldosteronism. The Merck Manuals Online Medical Library: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec12/ch153/ch153f.html. Accessed Sept. 25, 2008.
- Sechi LA. Long-term renal outcomes in patients with primary aldosteronism. Journal of the American Medical Association. 2006;295(22):2638-2645.
- Young WF, et al. Treatment of primary aldosteronism. http://www.uptodate.com/home/index.html. Accessed Sept. 25, 2008.
- Aldosterone and renin. Lab Tests Online. http://www.labtestsonline.org/understanding/analytes/aldosterone/test.html. Accessed Sept. 28, 2008.
- Young WF, et al. Clinical features of primary aldosteronism. http://www.uptodate.com/online/content/topic.do?topicKey=adrenal/19130&selectedTitle=3~56&source=search_result. Accessed Nov. 28, 2008.
- Young WF, et al. Treatment of primary aldosteronism. http://www.uptodate.com/online/content/topic.do?topicKey=adrenal/19430&selectedTitle=2~56&source=search_result. Accessed Nov. 28, 2008.
