Primary biliary cirrhosis

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Lifestyle and home remedies

By Mayo Clinic staff

Taking good care of your overall health may help you feel better and improve some of the symptoms of primary biliary cirrhosis:

  • Eat a reduced-sodium diet, because sodium increases your risk of tissue swelling and of accumulating fluid in your abdominal cavity (ascites).
  • Exercise and take calcium and vitamin D supplements to help reduce your risk of developing osteoporosis.
  • Avoid alcohol consumption, because it speeds the progression of liver disease.
  • Practice good skin care to reduce itching. Avoid scratching. Use cool, wet compresses. Try cool baking soda or oatmeal baths. Avoid irritating clothes, soaps and detergents.
  • Use artificial tears to help reduce dry eyes.
  • If you're a smoker, quit. Smoking may speed up the rate of liver scarring.
  • Check with your doctor before starting new medications or dietary supplements. Because you're liver isn't working normally, you'll likely be more sensitive to the effects of over-the-counter and prescription medications, as well as some dietary supplements, so check with your doctor before taking anything new.
References
  1. Primary biliary cirrhosis. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/primarybiliarycirrhosis/index.htm. Accessed Aug. 14, 2009.
  2. Primary biliary cirrhosis. American Liver Foundation. http://www.liverfoundation.org/education/info/pbc/. Accessed Aug. 14, 2009.
  3. Cirrhosis. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec03/ch026/ch026c.html. Accessed Aug. 14, 2009.
  4. Friedman LS. Liver, biliary tract and pancreas disorders. In: McPhee SJ, et al. Current Medical Diagnosis & Treatment. 48th ed. Los Altos, Calif.: Lange Medical Publications; 2009. http://www.accessmedicine.com/content.aspx?aID=7993. Accessed Aug. 14, 2009.
  5. Kaplan M, et al. Primary biliary cirrhosis. New England Journal of Medicine. 2005;353:1261.
  6. Kaplan MM. Clinical manifestations, diagnosis, and natural history of primary biliary cirrhosis. http://www.uptodate.com/home/index.html. Accessed July 30, 2009.
  7. Kaplan MM. Overview of the treatment of primary biliary cirrhosis. http://www.uptodate.com/home/index.html. Accessed July 30, 2009.
  8. Hirschfeld GM, et al. Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. New England Journal of Medicine. 2009;360:2544.
  9. Taouli B, et al. Advanced MRI methods for assessment of chronic liver disease. American Journal of Roentgenology. 2009;193:14.
  10. Lazaridis K, et al. Increased prevalence of antimitochondrial antibodies in first-degree relatives of patients with primary biliary cirrhosis. Hepatology. 2007;46:785.
  11. Lindor K. Ursodeoxycholic acid for the treatment of primary biliary cirrhosis. New England Journal of Medicine. 2007;357:1254.
  12. Picco MF (expert opinion). Mayo Clinic, Jacksonville, Fla. Aug. 31, 2009.
  13. Hay JE. Bone disease in cholestatic liver disease. Gastroenterology. 1995;108:278.

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Oct. 20, 2009

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