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By Mayo Clinic staffSeveral factors are known to increase your risk of developing CPPD crystals that can increase your risk of pseudogout, including:
- Older age. Older adults are more likely to experience pseudogout because CPPD crystals are more commonly found in the joints of older people.
- Joint trauma. Trauma to a joint, such as a serious injury or a joint replacement surgery, increases your risk of developing CPPD crystals in your joints.
- Genetic disorder. Families can pass predisposition to CPPD crystals through their genes. People with familial chondrocalcinosis, the name for the inherited condition, tend to develop signs and symptoms of CPPD crystal disease at younger ages.
- Excess iron stored in your body (hemochromatosis). This inherited disorder causes your body to store excess iron in your organs and the tissues around your joints. It's believed the iron in your joints leads to the development of CPPD crystals.