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By Mayo Clinic staffAntibiotics are used only when your doctor believes they're necessary; make sure you take them exactly as prescribed. Particularly if you've already had an episode of pseudomembranous colitis, be sure to discuss this disease history with your doctor before taking antibiotics again.
Some research suggests that the use of probiotics can prevent pseudomembranous colitis when used before, during and after treatment with antibiotics. The most commonly used probiotic in these circumstances is Saccharomyces boulardii (Florastor), which is more widely used in Europe than in the United States. Avoid this supplement if you have yeast allergies. While these probiotics are available over-the-counter, your doctor may prescribe them, especially if you have had recurrent infection.
You may still be positive for C. difficile for several weeks after you have responded to treatment and are feeling well. Although repeat treatment isn't usually needed in this case, you and your family should take strict precautions to avoid spreading the infection. Wash your hands frequently, sanitize your linens using hot water and bleach, and avoid sharing personal items such as razors, towels and clothing.