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By Mayo Clinic staffAntibiotic use is the key risk factor for pseudomembranous colitis. However, other risk factors include:
- Age older than 65 years
- Weakened immune system
- Diseases of the colon, such as inflammatory bowel disease and colorectal cancer
- Intestinal surgery
- Cancer chemotherapy with medications, such as 5-fluorouracil and cisplatin
Pseudomembranous colitis is more common in certain people in hospitals and nursing homes, often when they're receiving drugs or undergoing surgery in which antibiotics are part of the treatment regimen.