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Risk factors

By Mayo Clinic staff

Several factors can increase your risk of psoriatic arthritis, including:

  • Psoriasis. Having psoriasis is the single greatest risk factor for psoriatic arthritis. People who have psoriasis lesions on their nails are especially likely to develop psoriatic arthritis.
  • Your family history. Many people with psoriatic arthritis have a close relative with the disease.
  • Your age. Although anyone can develop psoriatic arthritis, it occurs most often in adults between the ages of 30 and 50.
  • Your sex. In general, psoriatic arthritis affects men and women equally, but DIP arthritis and spondylitis are more likely to affect men, whereas symmetric arthritis occurs more often in women.
References
  1. Questions and answers about psoriasis. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/hi/topics/psoriasis/psoriafs.htm. Accessed Sept. 9, 2008.
  2. Psoriatic arthritis. American College of Rheumatology. http://www.rheumatology.org/public/factsheets/psoriatic_new.asp. Accessed Sept. 9, 2008.
  3. Psoriasis of the nails. National Psoriasis Foundation. http://www.psoriasis.org/about/psoriasis/sites/nails.php. Accessed Sept. 9, 2008.
  4. Psoriatic arthritis. National Psoriasis Foundation. http://www.psoriasis.org/about/psa. Accessed Sept. 9, 2008.
  5. Gordon KB, et al. The treatment of psoriasis and psoriatic arthritis: An interdisciplinary approach. The Journal of the American Academy of Dermatology. 2006;54(3)(suppl):S85-S91.
  6. Cerhan JR, et al. Antioxidant micronutrients and risk of rheumatoid arthritis in a cohort of older women. American Journal of Epidemiology. 2003;157(4):345-354.
  7. Imokawa S, et al. Methotrexate pneumonitis: Review of the literature and histopathological findings in nine patients. The European Respiratory Journal. 2000;15(2):373-381.
  8. Tobin AM, et al. TNF alpha inhibitors in the treatment of psoriasis and psoriatic arthritis. BioDrugs. 2005;19(1):47-57.
  9. Gladman DD, et al. Patient information: Psoriatic arthritis. http://www.uptodate.com/home/index.html. Accessed Sept. 11, 2008.

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Dec. 13, 2008

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