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  • With Mayo Clinic behavioral counselor

    Jennifer A. Kern, M.S., C.T.T.S.

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  • Quit smoking blog

  • July 14, 2009

    Blog: Talk to your doctor about cessation drugs

    By Jennifer A. Kern, M.S., C.T.T.S.

6 comments posted

The FDA recently announced a new warning that will be placed on the packaging of the prescription drugs Chantix (Varenicline) and Zyban (Bupropion,Wellbutrin). They are adding the alert to both of these tobacco cessation medications due to reports of behavior changes being associated with their use in some individuals, including depressed mood, hostility or agitation, and suicidal thoughts or actions.

Although it's important to be aware of potential risks, I've found that the media coverage has been turning some people away from these medications, which have actually been helpful to many in reaching their goal of quitting smoking. 

Both Chantix and Zyban are intended to minimize symptoms of withdrawal by mimicking the effects of nicotine in the brain, and in many cases they are effective. Since they don't contain nicotine, however, people who use them to stop smoking may still experience withdrawal symptoms.  Some of the effects of nicotine withdrawal are the same as potential side effects from using Chantix or Zyban.

We know about half of all on-going smokers will die from tobacco-related diseases. The exact risks associated with the use of Chantix or Zyban aren't clear. It hasn't been proven that these medications actually cause abnormal behaviors, which is not to undermine concerns about adverse effects, but simply to make the distinction between association and causation.

The risks of continued smoking are high, and based on the FDA warnings, there are some risks of using Chantix or Zyban as well. The important thing is to talk with your doctor to evaluate your risks for using these medications. Compare them with the potential benefits of aiding you in becoming smoke-free, and then choose the best method for you.

6 comments posted

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July 14, 2009

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