Rebound headaches

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Risk factors

By Mayo Clinic staff

Risk factors for developing rebound headaches include:

  • History of chronic headaches. Anyone who has a history of migraines, tension-type headaches or other chronic headaches is at risk of developing rebound headaches from the overuse of pain relievers.
  • Frequent use of headache medications. Your risk increases if you use combination analgesics, ergotamine or triptans 10 or more days a month or simple analgesics more than 15 days a month — especially if this regular use continues for three or more months.

Rebound headaches aren't typically an issue for people who don't experience frequent headaches and use pain medications on a daily basis to treat other conditions such as arthritis.

References
  1. Zaza K, et al. Medication overuse headache. Current Neurology and Neuroscience Reports. 2009;9:115.
  2. Dodick DW, et al. How clinicians can detect, prevent and treat medication overuse headache. Cephalgia. 2008;28:1209.
  3. Vanderhoff BT, et al. Neurology. In: Rakel RE. Textbook of Family Medicine. 7th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/158911670-2/883980954/1481/600.html?printin. Accessed Sept. 5, 2009.
  4. Kaniecki R. Headache assessment and management. Journal of the American Medical Association. 2003;289:1430.
  5. Headache: Hope through research. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/headache/detail_headache.htm. Accessed Sept. 8, 2009.
  6. Dodick DW, et al. Evidence-based understanding of medication-overuse headache: Clinical implications. Headache. 2006;46:S202.
  7. Rappaport AM. Medication overuse headache: Awareness, detection, treatment. CNS Drugs. 2008;22:995.
  8. Sun-Edelstein C, et al. Complementary and alternative approaches to the treatment of tension-type headache. Current Pain and Headache Reports. 2008;12:447.
  9. Pandor SS, et al. Nonpharmacologic treatment of migraine. Current Pain and Headache Reports. 2005;9:202.
  10. Taylor FR. Headache prevention with complementary and alternative medicine. Headache. 2009;49:966.
  11. Garza I (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 13, 2009.
  12. Swanson JW (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 10, 2009.
  13. Bigal ME, et al. Acute migraine medications and evolution from episodic to chronic migraine: A longitudinal population-based study. Headache. 2008;48:1157.
  14. Smith TR, et al. Medication overuse headache from antimigraine therapy: Clinical features, pathogenesis and management. Drugs. 2004;64:2503.
  15. Young WB. Should Butalbital-containing analgesics be banned? Yes. Current Pain and Headache Reports. 2002;6:151.
  16. Silberstein SD, et al. Butalbital in the treatment of headache: History, pharmacology and efficacy. Headache. 2001;41:953.

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Dec. 8, 2009

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