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Risk factors
By Mayo Clinic staffThe following factors — usually when they occur together — may increase your child's risk of developing Reye's syndrome:
- Using aspirin to treat a viral infection, such as flu, chickenpox or an upper respiratory infection
- Having an underlying fatty acid oxidation disorder
References
- Gascon GG, et al. Aminoacidopathies and organic acidopathies, mitochondrial enzyme defects, and other metabolic errors. In: Goetz CG. Textbook of Clinical Neurology. 3rd ed. Philadelphia, Pa.: Elsevier Saunders; 2007. http://www.mdconsult.com/das/book/body/142707459-3/0/1488/274.html?tocnode=53802221&fromURL=274.html#4-u1.0-B978-1-4160-3618-0..10031-1_1989. Accessed June 10, 2009.
- Asturias EJ, et al. Postinfectious and vaccine-related encephalitis. In: Cohen J, et al. Infectious diseases. 2nd ed. Philadelphia, Pa.: Mosby; 2004. http://www.mdconsult.com/das/book/body/142707459-4/0/1209/82.html?tocnode=49352112&fromURL=82.html#4-u1.0-B0-323-02407-6..50029-5--cesec15_917. Accessed June 10, 2009.
- NINDS Reye's syndrome information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/reyes_syndrome/reyes_syndrome.htm. Accessed June 10, 2009.
- Carey RG, et al. Mitochondrial hepatopathies. In: Kliegman RM, et al. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa.: Elsevier Saunders; 2007. http://www.mdconsult.com/das/book/body/142707459-4/0/1608/857.html?tocnode=54481831&fromURL=857.html#4-u1.0-B978-1-4160-2450-7..50360-1_7094. Accessed June 10, 2009.
- Internal analgesic, antipyretic and antirheumatic drug products for over-the-counter human use: Tentative final monograph. Federal Register.1998;53:46204.
- Mahoney KR (expert opinion). U.S. Food and Drug Administration, Rockville, Md. Feb. 4, 2009.
- Recommended immunization schedules for persons aged 0-18 years - United States, 2009. Centers for Disease Control and Prevention. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5751a5.htm?s_cid=mm5751a5_e. Accessed June 10, 2009.
- Reye's syndrome. National Reye's Syndrome Foundation. http://www.reyessyndrome.org/pdfs/Awareness_Lists_English_full.pdf. Accessed June 16, 2009.
- Kawasaki disease. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=4634. Accessed June 17, 2009.
- Gosalakkal JA, et al. Reye syndrome and Reye-like syndrome. Pediatric Neurology, 2008;39:198.
- Renaud DL (expert opinion). Mayo Clinic, Rochester, Minn. July 6, 2009.
- Kamboj M. Clinical approach to the diagnoses of inborn errors of metabolism. Pediatric Clinics of North America. 2008;55:1113.
