• image.alt
  • With Mayo Clinic internist

    Sandhya Pruthi, M.D.

    read biography

Mayo Clinic Health Manager

Get free personalized health guidance for you and your family.

Get Started

Free

E-Newsletter

Subscribe to receive the latest updates on health topics. About our newsletters

  • Housecall
  • Alzheimer's caregiving
  • Living with cancer

Question

Semen allergy: A cause of infertility?

I often have a burning sensation in my vagina after my husband has ejaculated. My gynecologist has suggested I may have a semen allergy. How can I know for sure? Will this affect my ability to get pregnant?

Answer

from Sandhya Pruthi, M.D.

In rare cases, people have been known to have allergic reactions to proteins in their partner's semen (semen allergy). Semen allergy isn't a direct cause of infertility. However, using a condom, which is one of the most effective ways to prevent the allergic reaction, also prevents pregnancy.

Symptoms of semen allergy include redness, burning and swelling where the semen has contacted the skin, usually in the outer genital area. A small number of people may have a systemic response, including hives, itching and difficulty breathing. If you experience these signs and symptoms, see your doctor. He or she can help you determine whether you have a semen allergy. Allergy testing may be necessary.

If your sensitivity to semen is severe, you may still be able to get pregnant through artificial insemination using sperm washed free of semen proteins to prevent a reaction, or through in vitro fertilization.

Next question
Abnormal sperm morphology: What does it mean?

AN01225

Dec. 8, 2007

© 1998-2009 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Reliable tools for healthier lives," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Print Share Reprints

Text Size: smaller largerlarger