Mayo Clinic Health Manager
Get free personalized health guidance for you and your family.
Get StartedPreparing for your appointment
By Mayo Clinic staffBecause serotonin syndrome can be a life-threatening condition, seek emergency treatment right away if you have worsening or severe symptoms.
If your symptoms aren't severe, you're likely to start by first seeing your family doctor or a general practitioner. Because appointments can be brief, and because there's often a lot of ground to cover, it's a good idea to be well prepared for your appointment. Here's some information to help you get ready for your appointment, and what to expect from your doctor.
What you can do
- Be aware of any pre-appointment steps you need to take. At the time you make the appointment, be sure to ask if there's anything you need to do in advance, such as quitting any of the current medications or supplements you take.
- Write down any symptoms you're experiencing, including any that may seem unrelated to the reason for which you scheduled the appointment.
- Write down key personal information, including any major stresses or recent life changes.
- Make a list of all medications, as well as any vitamins or supplements that you're taking.
- Take a family member or friend along, if possible. Sometimes it can be difficult to soak up all the information provided to you during an appointment. Someone who accompanies you may remember something that you missed or forgot.
- Write down questions to ask your doctor.
Your time with your doctor is limited, so preparing a list of questions will help you make the most of your time together. List your questions from most important to least important in case time runs out. For symptoms you think may be caused by serotonin syndrome, some basic questions to ask your doctor include:
- Is serotonin syndrome most likely causing my symptoms, or could it be something else?
- Other than the most likely cause, what are other possible causes of my symptoms?
- What kinds of tests do I need?
- What is the best course of action?
- What are the alternatives to the primary approach that you're suggesting?
- I have these other health conditions. How can I best manage them together?
- Can I still take the medications I've been prescribed, or will I need to change them or change the dose?
- Are there any restrictions that I need to follow, such as avoiding certain drugs or supplements?
In addition to the questions that you've prepared to ask your doctor, don't hesitate to ask questions during your appointment at any time that you don't understand something.
What to expect from your doctor
Your doctor is likely to ask you a number of questions. Being ready to answer them may reserve time to go over any points you want to spend more time on. Your doctor may ask:
- When did you first begin experiencing symptoms?
- Have your symptoms been continuous, or occasional?
- How severe are your symptoms?
- What prescription and over-the-counter medications do you take?
- Do you use any illicit drugs?
- Do you take any dietary supplements?
- Moore DP. Serotonin syndrome. In: Moore DP. Moore & Jefferson: Handbook of Medical Psychiatry. 2nd ed. Philadelphia Pa.: Mosby; 2004. http://www.mdconsult.com/das/book/body/113440701-3/0/1243/148.html#4-u1.0-B0-323-02911-6..50148-2_1373. Accessed Dec. 10, 2008.
- Bilden EF, et al. Antidepressants. In: Marx JA: Rosen's Emergency Medicine: Concepts and Clinical Practice. 6th ed. Philadelphia Pa.: Elsevier; 2006. http://www.mdconsult.com/das/book/body/113410207-5/0/1365/463.html#4-u1.0-B0-323-02845-4..50154-2--cesec45_7826. Accessed Dec. 10, 2008.
- Boyer EW, et al. Serotonin syndrome. New England Journal of Medicine. 2005;352:1112.
- Combined use of 5-hydroxytryptamine receptor agonists (triptans), selective serotonin reuptake inhibitors (SSRIs) or selective serotonin/norepinephrine reuptake inhibitors (SNRIs) may result in life-threatening serotonin syndrome. US Food and Drug Administration. http://www.fda.gov/Cder/Drug/advisory/SSRI_SS200607.htm. Accessed Dec. 10, 2008.
- Zeping H, et al. Herb-drug interactions. Drugs. 2005;65:1239.
- Chyka PA, et al. Dextromethorphan poisoning: An evidence-based consensus guideline for out-of-hospital management. Clinical Toxicology. 2007;45:662.
- Argwal P. Serotonin syndrome. In: Ferri's Clinical Advisor 2009. Philadelphia, Pa.: Mosby Elsevier; 2009. http://www.mdconsult.com/das/book/body/113440701-3/0/1701/541.html#4-u1.0-B978-0-323-04134-8..50022-7--subchapter15_11410. Accessed Dec. 10, 2008