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Definition
By Mayo Clinic staffSjogren's (SHOW-grins) syndrome is a disorder of your immune system often defined by its two most common symptoms — dry eyes and a dry mouth.
Sjogren's syndrome often accompanies other autoimmune disorders, such as rheumatoid arthritis and lupus. In Sjogren's syndrome, the mucous membranes and moisture-secreting glands of your eyes and mouth are usually affected first — resulting in decreased production of tears and saliva.
Although you can develop Sjogren's syndrome at any age, most people are older than 40 at the time of diagnosis. The condition is much more common in women. Treatment focuses on relieving symptoms, which often subside with time.
- Questions and answers about Sjogren's syndrome. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Sjogrens_Syndrome/sjogrens_syndrome_qa.pdf. Accessed May 15, 2009.
- Kruszka P, et al. Diagnosis and management of Sjogren syndrome. American Family Physician. 2009;79:465.
- Naguwa S, et al. Sjogren's syndrome. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/137554062-3/841563606/1492/1035.html#4-u1.0-B978-1-4160-2805-5..50294-9_13050. Accessed May 15, 2009.
- Sjogren's syndrome. American College of Rheumatology. http://www.rheumatology.org/public/factsheets/diseases_and_conditions/sjogrens.asp. Accessed May 15, 2009.
- Fox R, et al. Treatment of Sjogren's syndrome. http://www.uptodate.com/home/index.html. Accessed May 20, 2009.
- Chang-Miller A (expert opinion). Mayo Clinic, Rochester, Minn. June 1, 2009.
