Statin drugs: Can they cause memory loss?

Is it true that statin drugs, such as Lipitor, can cause memory loss?

- Judy / Wisconsin

Mayo Clinic cardiologist Gerald Gau, M.D., and colleagues answer select questions from readers.

Answer

Rare cases of memory loss have been reported in people taking cholesterol-lowering statin drugs, such as Lipitor. But these reports were anecdotal and have not been substantiated by formal testing of cognitive function. In most of these cases, memory improved after the individuals stopped taking the statins. However, it's not clear whether the statin drugs caused the memory loss.

Although some studies suggest that statin drugs may actually reduce the risk of dementia, two large studies examining the potential health benefits of cholesterol-reducing medications found no effect on cognitive function from statins.

Keep in mind that any potential risk of memory loss from statins is very low compared with the proven benefits of statins in preventing heart attack and stroke. If you take statins and notice any changes in your memory, discuss your concerns with your doctor.