Thyroid disease: Can it affect a person's mood?

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    Todd B. Nippoldt, M.D.

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Question

Thyroid disease: Can it affect a person's mood?

Can thyroid disease affect a person's mood?

Answer

from Todd B. Nippoldt, M.D.

Yes, thyroid disease can affect a person's mood — primarily causing either anxiety or depression. Generally, the more severe the thyroid disease, the more severe the mood changes.

A person who has overactive thyroid (hyperthyroidism) may experience unusual nervousness, restlessness, anxiety and irritability. On the opposite end of the spectrum, a person who has underactive thyroid (hypothyroidism) may experience mild to severe fatigue and depression.

Still, it's unlikely that emotional symptoms such as anxiety or depression would be the only evidence of thyroid disease. Thyroid disease is usually associated with signs and symptoms such as weight gain or loss, sensitivity to hot or cold, bowel movement changes and menstrual irregularities.

Appropriate treatment — such as medication to block the body's ability to produce new thyroid hormone or replace missing thyroid hormone — usually improves both emotional and physical symptoms caused by thyroid disease.

References
  1. Hypothyroidism. American Thyroid Association. http://www.thyroid.org/patients/brochures/Hypo_brochure.pdf. Accessed Sept. 17, 2008.
  2. Hyperthyroidism. American Thyroid Association. http://www.thyroid.org/patients/brochures/Hyper_brochure.pdf. Accessed Sept. 17, 2008.
  3. Samuels MH. Cognitive function in untreated hypothyroidism and hyperthyroidism. Current Opinion in Endocrinology, Diabetes and Obesity. 2008;15:429.

AN00986

Dec. 13, 2008

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