Traveler's diarrhea

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Causes

By Mayo Clinic staff

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Illustration of the digestive system
The digestive system

It's possible that traveler's diarrhea may stem from the stress of traveling or a change in diet. But almost always an infectious agent is to blame.

You typically develop traveler's diarrhea after ingesting food or water that's contaminated with organisms from feces. These organisms are infectious agents — including various bacteria, viruses and parasites — that enter your gastrointestinal tract and overpower your defense mechanisms, resulting in signs and symptoms of traveler's diarrhea.

The most common cause of traveler's diarrhea is enterotoxigenic Escherichia coli (ETEC) bacteria. These bacteria attach themselves to the lining of your intestine and release a toxin that causes diarrhea and abdominal cramps.

So why aren't natives of high-risk countries affected in the same way? Often their bodies have become accustomed to the bacteria and developed immunity to them.

References
  1. Traveler's diarrhea. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dbmd/diseaseinfo/travelersdiarrhea_g.htm. Accessed April 21, 2009.
  2. Wanke CA. Traveler's diarrhea. http://www.uptodate.com/home/index.html. Accessed April 21, 2009.
  3. Traveler's diarrhea (turista). The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec02/ch016/ch016b.html. Accessed April 21, 2009.
  4. Snider CB, et al. Travel medicine. In: Rakel RE, et al. Conn's Current Therapy 2008. 60th ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/133386890-10/833243685/1621/89.html#4-u1.0-B978-1-4160-4435-2..50046-7_615. Accessed April 21, 2009.
  5. Burakoff R, et al. Gastrointestinal disease. In: Noble J, et al. Noble: Textbook of Primary Care Medicine. 3rd ed. St. Louis, Mo.: Mosby; 2001. http://www.mdconsult.com/das/book/body/133386890-12/0/959/648.html?tocnode=51449457&fromURL=648.html#4-u1.0-B0-323-00828-3..X5001-8--section10_3188. Accessed April 21, 2009.
  6. Traveler's health: Prevention of specific infectious diseases. Centers for Disease Control and Prevention. http://wwwn.cdc.gov/travel/yellowBookCh4-Diarrhea.aspx. Accessed April 21, 2009.
  7. First steps for managing an acute outbreak of diarrhoea. World Health Organization. http://www.who.int/topics/cholera/publications/en/first_steps.pdf. Accessed April 21, 2009.
  8. Norovirus: Q&A. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvrd/revb/gastro/norovirus-qa.htm. Accessed April 21, 2009.
  9. Sur DK, et al. Evaluating fever of unidentifiable source in young children. American Family Physician. 2007;75:1805.

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June 12, 2009

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