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By Mayo Clinic staffThe exact cause of tricuspid atresia is unknown, but several factors may increase the risk of a baby being born with this condition:
- A mother who had German measles (rubella) or another viral illness during early pregnancy
- A parent who has a congenital heart defect
- Excessive alcohol consumption during pregnancy
- A mother who has diabetes
- Use of some types of medications during pregnancy, such as the acne drug isotretinoin (Accutane) and lithium (Eskalith), which is used to treat bipolar disorder
Babies who have Down syndrome, a genetic condition that results from an extra 21st chromosome, also often have a congenital heart defect.