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  • With Mayo Clinic obstetrician and medical editor-in-chief

    Roger W. Harms, M.D.

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Mayo Clinic Health Manager

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Question

Vaccines during pregnancy: Are they safe?

I'm wondering about vaccines during pregnancy. Which vaccines are recommended during pregnancy? Which vaccines should be avoided?

Answer

from Roger W. Harms, M.D.

Generally, vaccines that contain inactivated (killed) viruses can be given during pregnancy. Vaccines that contain live viruses are not recommended for pregnant women.

The only vaccine routinely recommended during pregnancy is an influenza shot for women who are pregnant during flu season — typically November through March. The flu shot is made from an inactivated virus, so it's safe for both you and your baby. However, be sure to request the shot and not the nasal spray vaccine, which is made from a live virus.

Your health care provider may recommend a tetanus and diphtheria (Td) booster shot if you haven't had one in 10 or more years or if you have a deep cut during your pregnancy. Another form of the tetanus and diphtheria vaccine — called the Tdap — also offers protection from pertussis (whooping cough). Although the Tdap vaccine generally isn't given during pregnancy, your health care provider will likely recommend a Tdap vaccine as soon as the baby is born if you haven't had one before. In some cases, other vaccines are recommended after pregnancy as well.

If you're traveling abroad or you're at increased risk of certain infections, your health care provider may recommend other vaccines during pregnancy — such as hepatitis A, hepatitis B, meningococcal or pneumococcal vaccines.

In addition, certain vaccines are generally avoided during pregnancy, including:

  • Chickenpox (varicella)
  • Human papillomavirus (HPV)
  • Measles
  • Mumps
  • Rubella (German measles)
Next question
Breast-feeding while pregnant: Is it safe?
References
  1. Gerbie MV, et al. Pertussis disease in new mothers: Effect on young infants and strategies for prevention. Obstetrics and Gynecology. 2009;113:399.
  2. Immunization and pregnancy. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/pubs/downloads/f_preg.pdf. Accessed Feb. 26, 2009.
  3. Immunization and pregnancy. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/pubs/downloads/f_preg_chart.pdf. Accessed Feb. 26, 2009.
  4. Key facts about seasonal flu vaccine. Centers for Disease Control and Prevention. http://www.cdc.gov/flu/protect/keyfacts.htm. Accessed Feb. 26, 2009.

AN01886

March 27, 2009

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