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    James T. Li, M.D.

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Question

Vocal cord dysfunction: Is it a type of asthma?

What's the difference between vocal cord dysfunction and asthma?

Answer

from James T. Li, M.D.

Although they can have similar triggers and symptoms, vocal cord dysfunction is not the same as asthma.

  • With asthma, exposure to a lung irritant triggers the release of immune system chemicals that cause the airways (bronchial tubes) to tighten and produce excess mucus.
  • With vocal cord dysfunction, also called paradoxical vocal cord movement and laryngeal dysfunction, vocal cord muscles tighten and make breathing difficult. Unlike asthma, vocal cord dysfunction isn't an allergic reaction and doesn't involve the lower airways.

Because they have similar triggers and symptoms, it's common for vocal cord dysfunction to be misdiagnosed as asthma. This can lead to long-term use of asthma medications that don't help and in some cases cause serious side effects.

As with asthma, breathing in lung irritants, having an upper respiratory infection or exercising may trigger symptoms of vocal cord dysfunction. Both asthma and vocal cord dysfunction make breathing difficult and can cause coughing, wheezing, throat tightness and hoarseness. Unlike asthma, however, vocal cord dysfunction causes more difficulty breathing in than breathing out.

Doctors aren't sure what causes vocal cord dysfunction. Symptoms may appear after you've had a breathing tube in your throat, had certain anesthetic medications or if you have gastroesophageal reflux disease (GERD).

You may have vocal cord dysfunction and not asthma if your lungs have a normal response to asthma tests. These can include:

  • A lung-irritant test (methacholine challenge). Lower lung function test scores after breathing in methacholine are a sign that you may have asthma.
  • A nitric oxide test. This test measures the amount of nitric oxide gas in the air you breathe out. High levels of nitric oxide may be an indication of asthma.

Many people have both vocal cord dysfunction and asthma. Each may require separate treatment.

Vocal cord dysfunction generally improves with treatment, which can include learning deep-breathing techniques, learning to relax your throat muscles, speech therapy and psychotherapy to reduce stress.

Next question
Asthma without wheezing: Is this possible?
References
  1. Balkissoon RC, et al. Disorders of the upper airways. In: Mason RJ. Murray & Nadel's Textbook of Respiratory Medicine. 4th ed. Philadelphia, Pa.: Saunders Elsevier; 2005. http://www.mdconsult.com/das/book/body/156419261-3/0/1288/367.html?tocnode=51472411&fromURL=367.html#4-u1.0-B0-7216-0327-0..50043-4_2475. Accessed Aug. 25, 2009.
  2. Kelkar P, et al. Approach to the patient with chronic cough. In: Adkinson FM, et al. Middleton's Allergy: Principles and Practice. 7th ed. Philadelphia, Pa.: Mosby Elsevier. 2008. http://www.mdconsult.com/das/book/body/156419261-4/0/1806/83.html?tocnode=56311186&fromURL=83.html#4-u1.0-B978-0-323-05659-5..00079-6_2749. Accessed Aug. 25, 2009.

AN02020

Sept. 11, 2009

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