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By Mayo Clinic staffScabies treatment involves eliminating the infestation with medications. Several creams and lotions are available. You usually apply the medication over all your body, from your neck down, and leave the medication on for at least eight hours. Two medications commonly prescribed are permethrin (Elimite, Acticin) and crotamiton (Eurax). Although these medications kill the mites promptly, you may find that the itching doesn't stop entirely for several weeks.
Doctors sometimes prescribe oral medications for people with altered immune systems or for people who don't respond to the prescription lotions and creams.
Because scabies spreads so easily, your doctor may recommend treatment for all family members and other close contacts, even if they show no signs of scabies infestation.